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Delta-Aminolevulinic Acid Dehydratase (ALAD) Antibody
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Catalogue No: abx033007
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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The ALAD enzyme is composed of 8 identical subunits and catalyzes the condensation of 2 molecules of delta-aminolevulinate to form porphobilinogen (a precursor of heme, cytochromes and other hemoproteins). ALAD catalyzes the second step in the porphyrin and heme biosynthetic pathway; zinc is essential for enzymatic activity. ALAD enzymatic activity is inhibited by lead and a defect in the ALAD structural gene can cause increased sensitivity to lead poisoning and acute hepatic porphyria.
Research Articles on Delta-Aminolevulinic Acid Dehydratase (ALAD)
| Target | Delta-Aminolevulinic Acid Dehydratase (ALAD) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 244-272 amino acids from the C-terminal region of human ALAD. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P13716 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K375, B2R6F2, Q16870, Q16871, Q9BVQ9 |
| UniProt Entry Name | HEM2_HUMAN |
| KEGG | hsa:210 |
| String | 9606.ENSP00000386284 |
| Molecular Weight | Calculated MW: 36.3 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Monkey ALAD. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |