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Phosphoglycerate Kinase 1 (PGK1) Antibody
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Catalogue No: abx033171
Price:
US$326.25
(Size: 80 µl)
Orders to United States ship from United States
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Also known as ATP:3-phosphoglycerate 1-phosphotransferase (EC 2.7.2.3), this major enzyme in glycolysis catalyzes the reversible conversion of 1, 3-diphosphoglycerate to 3-phosphoglycerate, generating one molecule of ATP. New blood vessel formation or angiogenesis is critical for tumor expansion and metastasis. Lay et al. (2000) showed that the plasmin reductase isolated from conditioned medium of fibrosarcoma cells is the glycolytic enzyme phosphoglycerate kinase. They concluded that phosphoglycerate kinase not only functions in glycolysis but is secreted by tumor cells and participates in the angiogenic process as a disulfide reductase.
Research Articles on Phosphoglycerate Kinase 1 (PGK1)
| Target | Phosphoglycerate Kinase 1 (PGK1) |
| Clonality | Polyclonal |
| Reactivity | Human |
| Tested Applications | ELISA, WB, IHC, IF/ICC, FCM |
| Host | Rabbit |
| Recommended dilutions | WB: 1/1000, IHC-P: 1/100, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | KLH-conjugated synthetic peptide between 117-145 amino acids from the Central region of human PGK1. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P00558 (UniProt, ExPASy) |
| UniProt Secondary AC | A8K4W6, B7Z7A9, Q5J7W1, Q6IBT6, Q8NI87 |
| UniProt Entry Name | PGK1_HUMAN |
| NCBI Accession | NP_000282.1 |
| KEGG | hsa:5230 |
| String | 9606.ENSP00000362413 |
| Molecular Weight | Calculated MW: 44.6 kDa |
| Buffer | PBS containing 0.09% sodium azide. |
| Specificity | Predicted to react with Mouse, Rat, Horse and Monkey PGK1. |
| Availability | Shipped within 5-10 working days. |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |