Cyclin-Dependent Kinase Inhibitor P27 (27Kip1) Antibody

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Catalogue No: abx032765
Price: US$290.00
(Size: 80 µl)

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Datasheet SDS
p27Kip1 is a cyclin-dependent kinase inhibitor, which shares a limited similarity with CDK inhibitor CDKN1A/p21. The encoded protein binds to and prevents the activation of cyclin E-CDK2 or cyclin D-CDK4 complexes, and thus controls the cell cycle progression at G1. The degradation of this protein, which is triggered by its CDK dependent phosphorylation and subsequent ubiquitination by SCF complexes, is required for the cellular transition from quiescence to the proliferative state.

Target Cyclin-Dependent Kinase Inhibitor P27 (27Kip1)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/1000, IF/ICC: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 165-194 amino acids from the C-terminal region of human 27Kip1.
Isotype IgG
Form Liquid
Purification Purified through a protein A column, followed by peptide affinity purification.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P46527 (UniProt, ExPASy)
UniProt Secondary AC Q16307, Q5U0H2, Q9BUS6
UniProt Entry Name CDN1B_HUMAN
KEGG hsa:1027
String 9606.ENSP00000228872
Molecular Weight Calculated MW: 22.1 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Hamster CDKN1B.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cyclin-Dependent Kinase Inhibitor P27 (27Kip1)


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