Multidrug Resistance Associated Protein 1 (ABCC1) Antibody

Multidrug Resistance Associated Protein 1 (ABCC1) is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC gene are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts.

Target	Multidrug Resistance Associated Protein 1 (ABCC1)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1247-1275 amino acids from the C-terminal region of human ABCC1.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P33527 (UniProt, ExPASy)
UniProt Entry Name	MRP1_HUMAN
KEGG	hsa:4363
String	9606.ENSP00000382342
Molecular Weight	Calculated MW: 172 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Cow and Monkey ABCC1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Multidrug Resistance Associated Protein 1 (ABCC1)

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