Acid-Sensing Ion Channel 1 (ACCN2) Antibody

ACCN2 encodes a member of the degenerin/epithelial sodium channel (DEG/ENaC) superfamily. The members of this family are amiloride-sensitive sodium channels that contain intracellular N and C termini, 2 hydrophobic transmembrane regions, and a large extracellular loop, which has many cysteine residues with conserved spacing. The member is expressed in most if not all brain neurons, and it may be an ion channel subunit; however, its function as an ion channel remains unknown.

Target	Acid-Sensing Ion Channel 1 (ACCN2)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/50 - 1/100, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 500-526 amino acids from the C-terminal region of human ACCN2.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P78348 (UniProt, ExPASy)
UniProt Secondary AC	A3KN86, E5KBL7, P78349, Q96CV2
UniProt Entry Name	ASIC1_HUMAN
KEGG	hsa:41
String	9606.ENSP00000228468
Molecular Weight	Calculated MW: 59.9 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Mouse, Rat and Chicken ASIC1.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Acid-Sensing Ion Channel 1 (ACCN2)

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