Acetylcholinesterase (AChE) Antibody

Acetylcholinesterase hydrolyzes the neurotransmitter, acetylcholine at neuromuscular junctions and brain cholinergic synapses, and thus terminates signal transmission. The Protein is also found on the red blood cell membranes, where it constitutes the Yt blood group antigen. Acetylcholinesterase exists in multiple molecular forms which possess similar catalytic properties, but differ in their oligomeric assembly and mode of cell attachment to the cell surface. The major form of acetylcholinesterase found in brain, muscle and other tissues is the hydrophilic species, which forms disulfide-linked oligomers with collagenous, or lipid-containing structural subunits.

Target	Acetylcholinesterase (AChE)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, IF/ICC: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 147-175 amino acids from the N-terminal region of human ACHE.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P22303 (UniProt, ExPASy)
UniProt Entry Name	ACES_HUMAN
NCBI Accession	NP_000656.1 NP_001269378.1 NP_056646.1
KEGG	hsa:43
String	9606.ENSP00000303211
Molecular Weight	Calculated MW: 67.8 kDa
Buffer	PBS containing 0.09% sodium azide.
Specificity	Predicted to react with Guinea pig ACHE.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Acetylcholinesterase (AChE)

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