ATP Binding Cassette Transporter C3 (ABCC3) Antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MRP subfamily which is involved in multi-drug resistance. The specific function of this protein has not yet been determined; however, this protein may play a role in the transport of biliary and intestinal excretion of organic anions. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized.

Target	ATP Binding Cassette Transporter C3 (ABCC3)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Rabbit
Recommended dilutions	WB: 1/1000, IHC-P: 1/10 - 1/50, FCM: 1/10 - 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 899-925 amino acids from the Central region of human ABCC3.
Isotype	IgG
Form	Liquid
Purification	Purified through a protein A column, followed by peptide affinity purification.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15438 (UniProt, ExPASy)
UniProt Entry Name	MRP3_HUMAN
Gene Symbol	ABCC3
KEGG	hsa:8714
String	9606.ENSP00000285238
Molecular Weight	Calculated MW: 169 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on ATP Binding Cassette Transporter C3 (ABCC3)

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