Angiotensin I Converting Enzyme (ACE) Antibody

ACE is an enzyme involved in catalyzing the conversion of angiotensin I into a physiologically active peptide angiotensin II. Angiotensin II is a potent vasopressor and aldosterone-stimulating peptide that controls blood pressure and fluid-electrolyte balance. This enzyme plays a key role in the renin-angiotensin system. Many studies have associated the presence or absence of a 287 bp Alu repeat element in this gene with the levels of circulating enzyme or cardiovascular pathophysiologies. Two most abundant alternatively spliced variants of this gene encode two isozymes the somatic form and the testicular form that are equally active.

Target	Angiotensin I Converting Enzyme (ACE)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	ELISA, WB
Host	Rabbit
Recommended dilutions	WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	KLH-conjugated synthetic peptide between 1274-1306 amino acids from the C-terminal region of human ACE.
Isotype	IgG
Form	Liquid
Purification	Purified Rabbit Polyclonal Antibody.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P12821 (UniProt, ExPASy)
UniProt Secondary AC	B0LPF0, B4DXI3, E7EU16, P22966, Q53YX9, Q59GY8, Q7M4L4
UniProt Entry Name	ACE_HUMAN
KEGG	hsa:1636
String	9606.ENSP00000290866
Molecular Weight	Calculated MW: 150 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Angiotensin I Converting Enzyme (ACE)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue