5'-AMP-Activated Protein Kinase Subunit Beta-2 (AMPK beta 2) Antibody

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Catalogue No: abx033144
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit may be a positive regulator of AMPK activity. The myristoylation and phosphorylation of this subunit have been shown to affect the enzyme activity and cellular localization of AMPK. This subunit may also serve as an adaptor molecule mediating the association of the AMPK complex.

Target 5'-AMP-Activated Protein Kinase Subunit Beta-2 (AMPK beta 2)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB
Host Rabbit
Recommended dilutions WB: 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 3-33 amino acids from the N-terminal region of human AMPK beta2 (PRKAB2).
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC O43741 (UniProt, ExPASy)
UniProt Secondary AC A8K9V5, B4DH06, Q5VXY0
UniProt Entry Name AAKB2_HUMAN
KEGG hsa:5565
String 9606.ENSP00000254101
Molecular Weight Calculated MW: 30.3 kDa
Buffer PBS containing 0.09% sodium azide.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 5'-AMP-Activated Protein Kinase Subunit Beta-2 (AMPK beta 2)


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