6-Phosphofructo-2-Kinase/fructose-2,6-Bisphosphatase 1 (PFKFB1) Antibody

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Catalogue No: abx033907
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK).

Target 6-Phosphofructo-2-Kinase/fructose-2,6-Bisphosphatase 1 (PFKFB1)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 13-43 amino acids from the N-terminal region of human PFKFB1.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P16118 (UniProt, ExPASy)
UniProt Secondary AC B2RA88, B4DUN5, Q5JXS5, Q99951
UniProt Entry Name F261_HUMAN
KEGG hsa:5207
String 9606.ENSP00000364145
Molecular Weight Calculated MW: 54.7 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Rat and Cow PFKFB1.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 6-Phosphofructo-2-Kinase/fructose-2,6-Bisphosphatase 1 (PFKFB1)


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