14-3-3 Protein Beta/Alpha (YWHAB) Antibody

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Catalogue No: abx033917
Price: US$326.25
(Size: 80 µl)

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Datasheet SDS
YWHAB belongs to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants differing in the 5' UTR, but encoding the same protein, have been identified for the gene. Both variants encode the same protein, however, they are differentially expressed in hematopoietic cells.

Target 14-3-3 Protein Beta/Alpha (YWHAB)
Clonality Polyclonal
Reactivity Human
Tested Applications ELISA, WB, IHC
Host Rabbit
Recommended dilutions WB: 1/1000, IHC-P: 1/50 - 1/100. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen KLH-conjugated synthetic peptide between 56-85 amino acids from the N-terminal region of human YWHAB.
Isotype IgG
Form Liquid
Purification Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P31946 (UniProt, ExPASy)
UniProt Secondary AC A8K9K2, E1P616
UniProt Entry Name 1433B_HUMAN
NCBI Accession NP_003395.1 NP_647539.1
KEGG hsa:7529
String 9606.ENSP00000361930
Molecular Weight Calculated MW: 28.1 kDa
Buffer PBS containing 0.09% sodium azide.
Specificity Predicted to react with Mouse, Rat, Cow and Monkey YWHAB.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on 14-3-3 Protein Beta/Alpha (YWHAB)


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