Multidrug Resistance Associated Protein 1 (ABCC1) Antibody

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Catalogue No: abx002190
Price: US$203.00
(Size: 20 µl)

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Datasheet SDS
Multidrug Resistance Associated Protein 1 (ABCC1) Antibody is a Rabbit Polyclonal antibody against Multidrug Resistance Associated Protein 1 (ABCC1). The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra-and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This full transporter is a member of the MRP subfamily which is involved in multi-drug resistance. This protein functions as a multispecific organic anion transporter, with oxidized glutatione, cysteinyl leukotrienes, and activated aflatoxin B1 as substrates. This protein also transports glucuronides and sulfate conjugates of steroid hormones and bile salts. Alternatively spliced variants of this gene have been described but their full-length nature is unknown.

Target Multidrug Resistance Associated Protein 1 (ABCC1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/100 - 1/500, IHC-P: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein containing a sequence corresponding to amino acids 850-960 of human MRP1/ABCC1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P33527 (UniProt, ExPASy)
UniProt Entry Name MRP1_HUMAN
Gene Symbol ABCC1
GeneID 4363
NCBI Accession NP_004987.2
KEGG hsa:4363
String 9606.ENSP00000382342
Molecular Weight Calculated MW: 172 kDa
Observed MW: 170-220 kDa
Buffer PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration > 0.2 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Multidrug Resistance Associated Protein 1 (ABCC1)


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