Multidrug Resistance-Associated Protein 4 (ABCC4) Antibody

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters.ABC proteins transport various molecules across extra- and intra-cellular membranes.ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White).This protein is a member of the MRP subfamily which is involved in multi-drug resistance.The specific function of this protein has not yet been determined; however, this protein may play a role in cellular detoxification as a pump for its substrate, organic anions.Alternative splicing results in multiple splice variants encoding different isoforms.

Target	Multidrug Resistance-Associated Protein 4 (ABCC4)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, IHC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human ABCC4 (AA: 631-692) expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	O15439 (UniProt, ExPASy)
UniProt Secondary AC	A9Z1Z7, B7Z3Q7, Q8IVZ4, Q8IZN6, Q8NEW8, Q9Y6J2
UniProt Entry Name	MRP4_HUMAN
Gene Symbol	ABCC4
GeneID	10257
OMIM	605250
HGNC	55
KEGG	hsa:10257
Ensembl	ENSG00000125257
String	9606.ENSP00000366084
Molecular Weight	150 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Multidrug Resistance-Associated Protein 4 (ABCC4)

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