RAC-Beta Serine/threonine-Protein Kinase (AKT2) Antibody

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Catalogue No: abx010368
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
Akt2 (also designated protein kinase B beta or v-akt murine thymoma viral oncogene homolog 2), with 481-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt3. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake. Among the members of AKT family, Akt2 is associated with the development of human cancers. Akt2 inhibits cisplatin-induced JNK/p38 and Bax activation through phosphorylation of ASK1 and thus, plays an important role in chemoresistance. Further, Akt2 plays a specific role in muscle differentiation.

Target RAC-Beta Serine/threonine-Protein Kinase (AKT2)
Clonality Monoclonal
Reactivity Human, Rat, Monkey
Tested Applications ELISA, WB, IHC, IF/ICC
Host Mouse
Recommended dilutions ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human AKT2 expressed in E. coli.
Isotype IgG2b
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P31751 (UniProt, ExPASy)
UniProt Secondary AC B2RBD8, Q05BV0, Q0VAN0, Q0VAN1, Q68GC0
UniProt Entry Name AKT2_HUMAN
GeneID 208
KEGG hsa:208
String 9606.ENSP00000375892
Molecular Weight 60 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on RAC-Beta Serine/threonine-Protein Kinase (AKT2)


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