RAC-Gamma Serine/threonine-Protein Kinase (Akt3) Antibody

Akt3 (also designated protein kinase B gamma or v-akt murine thymoma viral oncogene homolog 3), with 479-amino acid protein (about 53kDa), belongs to the AKT serine/threonine protein kinase family, which also includes Akt1 and Akt2. AKT kinases are known to be regulators of cell signaling in response to insulin and growth factors. They are involved in a wide variety of biological processes including cell proliferation, differentiation, apoptosis, tumorigenesis, as well as glycogen synthesis and glucose uptake.Akt3 is not required for the maintenance of normal carbohydrate metabolism but is essential for the attainment of normal organ size. Identifying Akt3 as a selective target in melanoma cells also provides new therapeutic opportunities for patients in the advanced stages of this disease.

Target	RAC-Gamma Serine/threonine-Protein Kinase (Akt3)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA
Host	Mouse
Recommended dilutions	ELISA: 1/10000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of Akt3 expressed in E. coli.
Form	Liquid
Purification	Unpurified ascites.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q9Y243 (UniProt, ExPASy)
UniProt Secondary AC	Q0VAA6, Q5VTI1, Q5VTI2, Q96QV3, Q9UFP5
UniProt Entry Name	AKT3_HUMAN
Gene Symbol	AKT3
GeneID	10000
OMIM	611223
HGNC	393
Ensembl	ENSG00000117020
String	9606.ENSP00000263826
Enzyme Commission Number	EC 2.7.11.1 EC 2.7.11
Molecular Weight	55 kDa
Buffer	Ascitic fluid containing 0.03% sodium azide.
Concentration	Not determined.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on RAC-Gamma Serine/threonine-Protein Kinase (Akt3)

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