Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL) Antibody

There are at least four distinct but related alkaline phosphatases: intestinal, placental, placental-like, and liver/bone/kidney (tissue non-specific). The first three are located together on chromosome 2, while the tissue non-specific form is located on chromosome 1. The product of this gene is a membrane bound glycosylated enzyme that is not expressed in any particular tissue and is, therefore, referred to as the tissue-nonspecific form of the enzyme.

Target	Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, FCM
Host	Mouse
Recommended dilutions	ELISA: 1/10000, WB: 1/500 - 1/2000, IHC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Purified recombinant fragment of human ALPL expressed in E. coli.
Isotype	IgG1
Form	Liquid
Purification	Purified from ascites by Protein G chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P05186 (UniProt, ExPASy)
UniProt Entry Name	PPBT_HUMAN
Gene Symbol	ALPL
GeneID	249
OMIM	146300
HGNC	438
KEGG	hsa:249
Ensembl	ENSG00000162551
String	9606.ENSP00000363973
Molecular Weight	57.3 kDa
Buffer	PBS, containing 0.05% sodium azide.
Concentration	1 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Alkaline Phosphatase, Tissue-Nonspecific Isozyme (ALPL)

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