Adapter Molecule Crk (CRK) Antibody

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Catalogue No: abx011986
Price: US$420.50
(Size: 100 µl)

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Datasheet SDS
This gene encodes a member of an adapter protein family that binds to several tyrosine-phosphorylated proteins. The product of this gene has several SH2 and SH3 domains (src-homology domains) and is involved in several signaling pathways, recruiting cytoplasmic proteins in the vicinity of tyrosine kinase through SH2-phosphotyrosine interaction. The N-terminal SH2 domain of this protein functions as a positive regulator of transformation whereas the C-terminal SH3 domain functions as a negative regulator of transformation. Two alternative transcripts encoding different isoforms with distinct biological activity have been described.

Target Adapter Molecule Crk (CRK)
Clonality Monoclonal
Reactivity Human
Tested Applications ELISA, IHC, IF/ICC, FCM
Host Mouse
Recommended dilutions ELISA: 1/10000, IHC: 1/200 - 1/1000, IF/ICC: 1/200 - 1/1000, FCM: 1/200 - 1/400. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Purified recombinant fragment of human CRK expressed in E. coli.
Isotype IgG2b
Form Liquid
Purification Unpurified ascites.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P46108 (UniProt, ExPASy)
UniProt Secondary AC A8MWE8, B0LPE8, D3DTH6, Q96GA9, Q96HJ0
UniProt Entry Name CRK_HUMAN
Gene Symbol CRK
GeneID 1398
OMIM 164762
HGNC 2362
KEGG hsa:1398
Ensembl ENSG00000167193
String 9606.ENSP00000300574
Molecular Weight 42 kDa
Buffer Ascitic fluid containing 0.03% sodium azide.
Concentration Not determined.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Adapter Molecule Crk (CRK)


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