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ABL1 / 2 (pY393 / 429) Antibody

Catalogue No: abx000333
Price: £220.00
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ABL1/2 (pY393/429) Antibody is a Rabbit Polyclonal antibody against ABL1/2 (pY393/429). Regulates cytoskeleton remodeling during cell differentiation, cell division and cell adhesion. Localizes to dynamic actin structures, and phosphorylates CRK and CRKL, DOK1, and other proteins controlling cytoskeleton dynamics. Regulates DNA repair potentially by activating the proapoptotic pathway when the DNA damage is too severe to be repaired. Phosphorylates PSMA7 that leads to an inhibition of proteasomal activity and cell cycle transition blocks.

Target ABL1/2 (pY393/429)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y393/429 of human ABL1/2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P00519 (UniProt, ExPASy) P42684 (UniProt, ExPASy)
Gene Symbol ABL1, ABL2
GeneID 25/27
Molecular Weight Calculated MW: 122 kDa, 124 kDa, 60 kDa, 114-128 kDa
Observed MW: 210 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on ABL1 / 2 (pY393 / 429) Antibody

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