Acyl-CoA Synthetase Long-Chain Family Member 1 (ACSL1) Antibody

Catalogue No: abx000953
Price: £230.00
(Size: 50 µl)
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Acyl-CoA Synthetase Long-Chain Family Member 1 (ACSL1) Antibody

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ACSL1 Antibody is a Rabbit Polyclonal antibody against ACSL1. ACSL1(Long-chain-fatty-acid--CoA ligase 1) is also named as FACL1, FACL2, LACS, LACS1, LACS2 and belongs to the ATP-dependent AMP-binding enzyme family. ACSL1 is a 75 kDa protein that is associated peripherally with the plasma membrane(Brian M Wiczer, etc., 2006). ACSL1 is abundantly expressed in tissues, such as liver and brown fat, that metabolize substantial amounts of triglycerides as fuel, and as such, a deficiency in ACSL1 function could have a more profound affect in those cells, resulting in hepatosteatosis and potentially increased very low density lipoprotein production by the liver or decreased thermogenic capacity in brown adipose tissue(PMID:19429676). An anti-rat ACSL1 antibody recognized a band of the predicted 68 kDa in high-speed supernatant from rat liver and in human and murine SMCs, monocyte-derived macrophages, and murine peritoneal macrophages(PMID:17259370). It has 2 isoforms produced by alternative splicing. This antibody is specific to ACSL1.

Target Acyl-CoA Synthetase Long-Chain Family Member 1 (ACSL1)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/200 - 1/1000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human ACSL1.
Isotype IgG
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P33121 (UniProt, ExPASy)
UniProt Secondary AC B7Z452, D3DP57, P41215, Q8N8V7, Q8TA99
UniProt Entry Name ACSL1_HUMAN
GeneID 2180
KEGG hsa:2180
String 9606.ENSP00000422607
Molecular Weight 78 kDa
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH 7.3.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Acyl-CoA Synthetase Long-Chain Family Member 1 (ACSL1) Antibody

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