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AMPK alpha (pT172) Antibody
Catalogue No: abx000170
Price:
£120.00
(Size: 20 µl)
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AMPKα (pT172) Antibody is a Rabbit Polyclonal antibody against AMPKα (pT172). The protein encoded by this gene belongs to the ser/thr protein kinase family. It is the catalytic subunit of the 5'-prime-AMP-activated protein kinase (AMPK). AMPK is a cellular energy sensor conserved in all eukaryotic cells. The kinase activity of AMPK is activated by the stimuli that increase the cellular AMP/ATP ratio. AMPK regulates the activities of a number of key metabolic enzymes through phosphorylation. It protects cells from stresses that cause ATP depletion by switching off ATP-consuming biosynthetic pathways. Alternatively spliced transcript variants encoding distinct isoforms have been observed.
Research Articles on AMPK alpha (pT172)
| Target | AMPK alpha (pT172) |
| Clonality | Polyclonal |
| Reactivity | Mouse |
| Tested Applications | WB |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S172 of human AMPKα. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | Q13131 (UniProt, ExPASy) P54646 (UniProt, ExPASy) |
| UniProt Secondary AC | A8MTQ6, B2R7E1, O00286, Q5D0E1, Q86VS1, Q9UNQ4 |
| UniProt Entry Name | AAPK1_HUMAN |
| Gene Symbol | PRKAA1, PRKAA2 |
| GeneID | 5562 |
| String | 9606.ENSP00000346148 |
| Molecular Weight | Calculated MW: 64 kDa, 65 kDa Observed MW: 64 kDa |
| Buffer | PBS with 0.02% sodium azide, 50% glycerol, pH 7.3. |
| Concentration | > 1 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
