Apelin Receptor (APLNR) Antibody

APLNR Antibody is a Rabbit Polyclonal antibody against APLNR. This gene encodes a member of the G protein-coupled receptor gene family. The encoded protein is related to the angiotensin receptor, but is actually an apelin receptor that inhibits adenylate cyclase activity and plays a counter-regulatory role against the pressure action of angiotensin II by exerting hypertensive effect. It functions in the cardiovascular and central nervous systems, in glucose metabolism, in embryonic and tumor angiogenesis and as a human immunodeficiency virus (HIV-1) coreceptor. Two transcript variants resulting from alternative splicing have been identified.

Target	Apelin Receptor (APLNR)
Clonality	Polyclonal
Reactivity	Human
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/200 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 301-380 of human APLNR.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P35414 (UniProt, ExPASy)
UniProt Entry Name	APJ_HUMAN
Gene Symbol	APLNR
GeneID	187
NCBI Accession	NP_005152.1
KEGG	hsa:187
String	9606.ENSP00000475344
Molecular Weight	Calculated MW: 43 kDa Observed MW: 43 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Apelin Receptor (APLNR)

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