ARRB2 Antibody

Catalogue No: abx000571
Price: $364.00
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ARRB2 Antibody

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ARRB2 Antibody is a Rabbit Polyclonal antibody against ARRB2. Members of arrestin/beta-arrestin protein family are thought to participate in agonist-mediated desensitization of G-protein-coupled receptors and cause specific dampening of cellular responses to stimuli such as hormones, neurotransmitters, or sensory signals. ARRB2, like arrestin beta 1, was shown to inhibit beta-adrenergic receptor function in vitro. It is expressed at high levels in the central nervous system and may play a role in the regulation of synaptic receptors. Besides the brain, a cDNA for ARRB2 was isolated from thyroid gland, and thus it may also be involved in hormone-specific desensitization of TSH receptors. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target ARRB2
Reactivity Human, Mouse
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human ARRB2.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 46 kDa
Swiss Prot P32121
GeneID 409
Gene Symbol ARRB2
OMIM 107941
HGNC 712
Ensembl ENSG00000141480
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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