ATF2 (pT71/T53) Antibody is a Rabbit Polyclonal antibody against ATF2 (pT71/T53). This gene encodes a transcription factor that is a member of the leucine zipper family of DNA binding proteins. This protein binds to the cAMP-responsive element (CRE), an octameric palindrome. It forms a homodimer or a heterodimer with c-Jun and stimulates CRE-dependent transcription. This protein is also a histone acetyltransferase (HAT) that specifically acetylates histones H2B and H4 in vitro; thus it may represent a class of sequence-specific factors that activate transcription by direct effects on chromatin components. Several alternatively spliced transcript variants have been found for this gene.
| Target |
ATF2 (pT71/T53) |
| Reactivity |
Human, Mouse, Rat |
| Origin |
Human |
| Host |
Rabbit |
| Clonality |
Polyclonal |
| Tested Applications |
WB, IHC |
| Recommended dilutions |
WB: 1/500 - 1/2000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Immunogen |
Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T71/T53 of human ATF2. |
| Purification |
Affinity purified. |
| Form |
Liquid |
| Isotype |
IgG |
| Conjugation |
Unconjugated |
| Storage |
Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles. |
| Molecular Weight |
Calculated MW: 13- 15 kDa/23-24 kDa/35-54 kDa
Observed MW: 75 kDa |
| Swiss Prot |
P15336
|
| GeneID |
1386
|
| Gene Symbol |
ATF2 |
| Concentration |
> 1 mg/ml |
| Buffer |
PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Availability |
Shipped within 5-10 working days. |
| Note |
This product is for research use only. |
+44 (0) 1223 755950 /
United States
(
