V-Type Proton ATPase Subunit D 1 (ATP6V0D1) Antibody

ATP6V0D1 Antibody is a Rabbit Polyclonal antibody against ATP6V0D1. This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is known as the D subunit and is found ubiquitously.

Target	V-Type Proton ATPase Subunit D 1 (ATP6V0D1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-351 of human ATP6V0D1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P61421 (UniProt, ExPASy)
UniProt Secondary AC	P12953, Q02547
UniProt Entry Name	VA0D1_HUMAN
Gene Symbol	ATP6V0D1
GeneID	9114
NCBI Accession	NP_004682.2
KEGG	hsa:9114
String	9606.ENSP00000290949
Molecular Weight	Calculated MW: 40 kDa Observed MW: 40 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on V-Type Proton ATPase Subunit D 1 (ATP6V0D1)

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