Platelet And Endothelial Cell Adhesion Molecule 1 (PECAM1) Antibody

Catalogue No: abx200221
Price: £200.00
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Human CD31 is an adhesion molecule expressed on platelets, endothelial cells, leukocytes and their bone marrow precursors. CD31 plays a role in homophilic adhesion and heterophilic transendothelial migration. Antibody TP1/15 reacts with domain 1 of CD31 and blocks homophilic interaction and heterophilic transendothelial migration. Expressed diffusely by monocytes, neutrophils, and NK cells. Expressed on subsets of T cells.

Target CD31
Reactivity Human
Host Mouse
Tested Applications FCM
Recommended dilutions FCM: 20 μl/1 million cells. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Native purified PECAM1 from humanmyeloid leukemia cell line (RC-2A).
Purification Affinity Chromatography
Form Liquid
Isotype IgG2a
Conjugation Unconjugated
Specificity CD31 is a 130-140 kD type I transmembrane glycoprotein also known as platelet endothelial cell adhesion molecule-1 (PECAM-1) or Endocam. It is expressed on monocytes, platelets, granulocytes, endothelial cells and lymphocyte subsets. CD31 has been reported to bind CD38 and be involved in wound healing, angiogenesis, and cellular migration in an inflammatory situation.
Storage Store in the dark at 2-8 °C.
Molecular Weight 130-140 kDa
Swiss Prot P16284
GeneID 5175
Buffer The reagent is provided in aqueous buffered solution containing protein stabilizer, and ≤0.09% sodium Azide
UNSPSC Code 12352203
Availability Shipped within 2-3 weeks.
Note This product is for research use only.

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