CD44 Antigen (CD44) Antibody

The protein encoded by this gene is a cell-surface glycoprotein involved in cell-cell interactions, cell adhesion and migration. It is a receptor for hyaluronic acid (HA) and can also interact with other ligands, such as osteopontin, collagens, and matrix metalloproteinases (MMPs). This protein participates in a wide variety of cellular functions including lymphocyte activation, recirculation and homing, hematopoiesis, and tumor metastasis. Transcripts for this gene undergo complex alternative splicing that results in many functionally distinct isoforms, however, the full length nature of some of these variants has not been determined. Alternative splicing is the basis for the structural and functional diversity of this protein, and may be related to tumor metastasis.

Target	CD44 Antigen (CD44)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB, IHC, IF/ICC, FCM
Host	Mouse
Recommended dilutions	WB: 1/2000, IHC-P: 1/25, IF/ICC: 1/10 - 1/50, FCM: 1/50. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Human CD44 recombinant protein.
Isotype	IgG2a Kappa
Form	Liquid
Purification	Purified through a protein G column, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P16070 (UniProt, ExPASy)
Gene Symbol	CD44
GeneID	960
Molecular Weight	Calculated MW: 81.5 kDa
Buffer	PBS containing 0.09% sodium azide.
Concentration	0.42 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on CD44 Antigen (CD44)

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