CDH1 Antibody

Catalogue No: abx000082
Price: £220.00
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CDH1 Antibody is a Mouse Monoclonal antibody against CDH1. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Target CDH1
Reactivity Human
Origin Human
Host Mouse
Clonality Monoclonal
Tested Applications IHC
Recommended dilutions IHC: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human CDH1.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Swiss Prot P12830
GeneID 999
Gene Symbol CDH1
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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