Menu

Cadherin-1 / E-Cadherin (CDH1) Antibody

Catalogue No: abx000082
Price: £220.00
Reviews: 0 reviews
(0 reviews)

Available Options

* Size:



CDH1 Antibody is a Mouse Monoclonal antibody against CDH1. This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Mutations in this gene are correlated with gastric, breast, colorectal, thyroid and ovarian cancer. Loss of function is thought to contribute to progression in cancer by increasing proliferation, invasion, and/or metastasis. The ectodomain of this protein mediates bacterial adhesion to mammalian cells and the cytoplasmic domain is required for internalization. Identified transcript variants arise from mutation at consensus splice sites.

Target Cadherin-1 / E-Cadherin (CDH1)
Clonality Monoclonal
Reactivity Human
Tested Applications IHC
Host Mouse
Recommended dilutions IHC: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CDH1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UNSPSC Code 12352203
UniProt Primary AC P12830
Gene Symbol CDH1
GeneID 999
Molecular Weight Calculated MW: 90 kDa, 97 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cadherin-1 / E-Cadherin (CDH1) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)