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Cyclin-Dependent Kinase 6 (CDK6) Antibody

Catalogue No: abx001301
Price: £160.00
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Cyclin-Dependent Kinase 6 (CDK6) Antibody Cyclin-Dependent Kinase 6 (CDK6) Antibody Cyclin-Dependent Kinase 6 (CDK6) Antibody Cyclin-Dependent Kinase 6 (CDK6) Antibody Cyclin-Dependent Kinase 6 (CDK6) Antibody Cyclin-Dependent Kinase 6 (CDK6) Antibody Cyclin-Dependent Kinase 6 (CDK6) Antibody

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CDK6 Antibody is a Rabbit Polyclonal antibody against CDK6. The protein encoded by this gene is a member of the cyclin-dependent protein kinase (CDK) family. CDK family members are highly similar to the gene products of Saccharomyces cerevisiae cdc28, and Schizosaccharomyces pombe cdc2, and are known to be important regulators of cell cycle progression. This kinase is a catalytic subunit of the protein kinase complex that is important for cell cycle G1 phase progression and G1/S transition. The activity of this kinase first appears in mid-G1 phase, which is controlled by the regulatory subunits including D-type cyclins and members of INK4 family of CDK inhibitors. This kinase, as well as CDK4, has been shown to phosphorylate, and thus regulate the activity of, tumor suppressor protein Rb. Expression of this gene is up-regulated in some types of cancer. Multiple alternatively spliced variants, encoding the same protein, have been identified.

Target CDK6
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CDK6.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q00534 (UniProt, ExPASy)
UniProt Secondary AC A4D1G0
UniProt Entry Name CDK6_HUMAN
Gene Symbol CDK6
GeneID 1021
String 9606.ENSP00000265734
Molecular Weight Calculated MW: 36 kDa
Observed MW: 37 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cyclin-Dependent Kinase 6 (CDK6) Antibody

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