Cyclin Dependent Kinase Inhibitor 1C (CDKN1C) Antibody

CDKN1C Antibody is a Rabbit Polyclonal antibody against CDKN1C. This gene is imprinted, with preferential expression of the maternal allele. The encoded protein is a tight-binding, strong inhibitor of several G1 cyclin/Cdk complexes and a negative regulator of cell proliferation. Mutations in this gene are implicated in sporadic cancers and Beckwith-Wiedemann syndorome, suggesting that this gene is a tumor suppressor candidate. Three transcript variants encoding two different isoforms have been found for this gene.

Target	Cyclin Dependent Kinase Inhibitor 1C (CDKN1C)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-107 of human CDKN1C/p57 Kip2.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P49918 (UniProt, ExPASy)
UniProt Entry Name	CDN1C_HUMAN
Gene Symbol	CDKN1C
GeneID	1028
NCBI Accession	NP_000067.1
KEGG	hsa:1028
String	9606.ENSP00000413720
Molecular Weight	Calculated MW: 32 kDa Observed MW: 57 kDa
Buffer	PBS, pH 7.3, containing 0.05% Proclin-300, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Cyclin Dependent Kinase Inhibitor 1C (CDKN1C)

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