Chloride Channel Protein ClC-Ka (CLCNKA) Antibody

CLCNKA Antibody is a Rabbit Polyclonal antibody against CLCNKA. This gene is a member of the CLC family of voltage-gated chloride channels. The encoded protein is predicted to have 12 transmembrane domains, and requires a beta subunit called barttin to form a functional channel. It is thought to function in salt reabsorption in the kidney and potassium recycling in the inner ear. The gene is highly similar to CLCNKB, which is located 10 kb downstream from this gene. Multiple transcript variants encoding different isoforms have been found for this gene.

Target	Chloride Channel Protein ClC-Ka (CLCNKA)
Clonality	Polyclonal
Reactivity	Human, Mouse
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 470-644 of human CLCNKA.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P51800 (UniProt, ExPASy)
UniProt Secondary AC	B4DPD3, E7EPH6, Q5T5P8, Q5T5Q4, Q7Z6D1, Q86VT1
UniProt Entry Name	CLCKA_HUMAN
Gene Symbol	CLCNKA
GeneID	1187
NCBI Accession	NP_001244068.1
KEGG	hsa:1187
String	9606.ENSP00000332771
Molecular Weight	Calculated MW: 75 kDa Observed MW: 75 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Chloride Channel Protein ClC-Ka (CLCNKA)

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