Complement C3 (C3) Antibody (Biotin)

Catalogue No: abx105282
Price: £130.00
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Complement C3 (C3) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Complement C3. C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.

Target Complement C3 (C3)
Clonality Polyclonal
Reactivity Mouse
Tested Applications ELISA
Host Rabbit
Recommended dilutions Optimal dilutions/concentrations should be determined by the end user.
Conjugation Biotin
Immunogen Recombinant mouse Complement C3 protein (1321-1663AA).
Isotype IgG
Form Liquid
Purity > 95%
Purification Protein G.
Storage Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01027 (UniProt, ExPASy)
UniProt Secondary AC Q61370, Q80XP1
UniProt Entry Name CO3_MOUSE
Gene Symbol C3
GeneID 12266
NCBI Accession NP_033908.2 NM_009778.3
KEGG mmu:12266
Ensembl ENSMUSG00000024164
String 10090.ENSMUSP00000024988
Buffer 0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Complement C3 (C3) Antibody (Biotin)

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