CTTN (pY466) Antibody

Catalogue No: abx000299
Price: £220.00
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CTTN (pY466) Antibody is a Rabbit Polyclonal antibody against CTTN (pY466). This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: regulating the interactions between components of adherens-type junctions and organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Target CTTN (pY466)
Reactivity Human, Mouse
Host Rabbit
Clonality Polyclonal
Tested Applications WB
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y466 of human CTTN.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 57 kDa/61 kDa/70 kDa
Observed MW: 80 kDa
Swiss Prot Q14247
GeneID 2017
Gene Symbol CTTN
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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