CTTN (pY466) Antibody

Catalogue No: abx000299
Price: £230.00
(Size: 50 µl)
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CTTN (pY466) Antibody

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CTTN (pY466) Antibody is a Rabbit Polyclonal antibody against CTTN (pY466). This gene is overexpressed in breast cancer and squamous cell carcinomas of the head and neck. The encoded protein is localized in the cytoplasm and in areas of the cell-substratum contacts. This gene has two roles: regulating the interactions between components of adherens-type junctions and organizing the cytoskeleton and cell adhesion structures of epithelia and carcinoma cells. During apoptosis, the encoded protein is degraded in a caspase-dependent manner. The aberrant regulation of this gene contributes to tumor cell invasion and metastasis. Three splice variants that encode different isoforms have been identified for this gene.

Target CTTN (pY466)
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y466 of human CTTN.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q14247 (UniProt, ExPASy)
UniProt Secondary AC Q8N707, Q96H99
UniProt Entry Name SRC8_HUMAN
Gene Symbol CTTN
GeneID 2017
KEGG hsa:2017
Molecular Weight Calculated MW: 57 kDa, 61 kDa, 70 kDa
Observed MW: 80 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on CTTN (pY466) Antibody

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