Menu

Cytochrome P450 3A5 (CYP3A5) Antibody

Catalogue No: abx001196
Price: £260.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Available Options

* Size:


CYP3A5 Antibody is a Rabbit Polyclonal antibody against CYP3A5. This gene,CYP3A5, encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and its expression is induced by glucocorticoids and some pharmacological agents. The enzyme metabolizes drugs such as nifedipine and cyclosporine as well as the steroid hormones testosterone, progesterone and androstenedione. This gene is part of a cluster of cytochrome P450 genes on chromosome 7q21.1. This cluster includes a pseudogene, CYP3A5P1, which is very similar to CYP3A5. This similarity has caused some difficulty in determining whether cloned sequences represent the gene or the pseudogene. Multiple alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Jun 2010].

Target CYP3A5
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human CYP3A5.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC Q86WB0 (UniProt, ExPASy)
UniProt Entry Name NIPA_HUMAN
Gene Symbol ZC3HC1
GeneID 1577
KEGG hsa:5153
String 9606.ENSP00000351052
Molecular Weight Calculated MW: 15 kDa, 57 kDa
Observed MW: 50 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Cytochrome P450 3A5 (CYP3A5) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)