E2F1 Antibody

Catalogue No: abx000534
Price: $364.00
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E2F1 Antibody

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E2F1 Antibody is a Rabbit Polyclonal antibody against E2F1. DNA tumor viruses appear to have transforming activity due to their binding and inactivating to the RB1 gene products, and transcription facotr E2F, which is first identified as a DNA-binding protein essential for E1A-dependent activation of the advenovirus E2 promoter. The complex DRTF1/E2F involves in the control of cell-cycle progression from G1 to S phase. E2F1, one of E2F preferentially binds to RB1 protein in a cell-cycle dependent manner. It mediates both cell proliferation and p53-dependent apoptosis.

Target E2F1
Reactivity Human, Mouse, Rat
Origin Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB
Recommended dilutions WB: 1/500 - 1/1000, IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human E2F1.
Purification Affinity purified.
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20 °C. Avoid repeated freeze/thaw cycles.
Molecular Weight 47 kDa
Swiss Prot Q01094
GeneID 1869
Gene Symbol E2F1
Concentration > 1 mg/ml
Buffer PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Availability Shipped within 5-10 working days.
Note This product is for research use only.

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