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EIF2AK2 (pT451) Antibody

Catalogue No: abx000388
Price: £220.00
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Immunohistochemistry of paraffin-embedded human colon carcinoma using Phospho-EIF2AK2-T451 antibody (abx000388).

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EIF2AK2 (pT451) Antibody is a Rabbit Polyclonal antibody against EIF2AK2 (pT451). The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene.

Target EIF2AK2 (pT451)
Clonality Polyclonal
Reactivity Human
Tested Applications IHC
Host Rabbit
Recommended dilutions IHC: 1/50 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding T451 of human EIF2AK2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P19525 (UniProt, ExPASy)
UniProt Secondary AC A8K3P0, D6W584, E9PC80, Q52M43, Q7Z6F6, Q9UIR4
UniProt Entry Name E2AK2_HUMAN
Gene Symbol EIF2AK2
GeneID 5610
String 9606.ENSP00000233057
Molecular Weight Calculated MW: 57 kDa, 62 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on EIF2AK2 (pT451) Antibody

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