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EIF2S1 (pS51) Antibody

Catalogue No: abx000390
Price: £230.00
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EIF2S1 (pS51) Antibody EIF2S1 (pS51) Antibody EIF2S1 (pS51) Antibody

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EIF2S1 (pS51) Antibody is a Rabbit Polyclonal antibody against EIF2S1 (pS51). The translation initiation factor EIF2 catalyzes the first regulated step of protein synthesis initiation, promoting the binding of the initiator tRNA to 40S ribosomal subunits. Binding occurs as a ternary complex of methionyl-tRNA, EIF2, and GTP. EIF2 is composed of 3 nonidentical subunits, the 36-kD EIF2-alpha subunit (EIF2S1), the 38-kD EIF2-beta subunit (EIF2S2; MIM 603908), and the 52-kD EIF2-gamma subunit (EIF2S3; MIM 300161). The rate of formation of the ternary complex is modulated by the phosphorylation state of EIF2-alpha (Ernst et al., 1987.

Target EIF2S1 (pS51)
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/100, IF/ICC: 1/100 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S51 of human EIF2S1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P05198 (UniProt, ExPASy)
UniProt Entry Name IF2A_HUMAN
Gene Symbol EIF2S1
GeneID 1965
KEGG hsa:1965
String 9606.ENSP00000256383
Molecular Weight Calculated MW: 36 kDa
Observed MW: 38 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on EIF2S1 (pS51) Antibody

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