Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1) Antibody

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq].

Target	Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1)
Clonality	Monoclonal
Reactivity	Human
Tested Applications	ELISA, WB
Host	Mouse
Recommended dilutions	WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Human EIF4EBP1 recombinant protein.
Isotype	IgG1 Kappa
Form	Liquid
Purification	Purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q13541 (UniProt, ExPASy)
UniProt Secondary AC	B2R502, D3DSW8, Q6IBN3
UniProt Entry Name	4EBP1_HUMAN
KEGG	hsa:1978
String	9606.ENSP00000340691
Molecular Weight	Calculated MW: 12.6 kDa
Buffer	PBS containing 0.09% sodium azide.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Eukaryotic Translation Initiation Factor 4E Binding Protein 1 (EIF4EBP1)

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