Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation 2 (ERCC2) Antibody

Catalogue No: abx001190
Price: £260.00
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ERCC2 Antibody is a Rabbit Polyclonal antibody against ERCC2. The nucleotide excision repair pathway is a mechanism to repair damage to DNA. The protein encoded by this gene is involved in transcription-coupled nucleotide excision repair and is an integral member of the basal transcription factor BTF2/TFIIH complex. The gene product has ATP-dependent DNA helicase activity and belongs to the RAD3/XPD subfamily of helicases. Defects in this gene can result in three different disorders, the cancer-prone syndrome xeroderma pigmentosum complementation group D, trichothiodystrophy, and Cockayne syndrome. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

Target ERCC2
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/200 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant fusion protein of human ERCC2.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P18074 (UniProt, ExPASy)
UniProt Secondary AC Q2TB78, Q2YDY2, Q7KZU6, Q8N721
UniProt Entry Name ERCC2_HUMAN
Gene Symbol ERCC2
GeneID 2068
String 9606.ENSP00000375809
Molecular Weight Calculated MW: 46 kDa, 86 kDa
Observed MW: 87 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Excision Repair Cross-Complementing Rodent Repair Deficiency, Complementation 2 (ERCC2) Antibody

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