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Fibrillarin (FBL) Antibody
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Catalogue No: abx001050
Price:
£120.00
(Size: 20 µl)
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FBL Antibody is a Rabbit Polyclonal antibody against FBL. This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.
Research Articles on Fibrillarin (FBL)
| Target | Fibrillarin (FBL) |
| Clonality | Polyclonal |
| Reactivity | Human, Mouse, Rat, Monkey |
| Tested Applications | WB, IF/ICC, IP |
| Host | Rabbit |
| Recommended dilutions | WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user. |
| Conjugation | Unconjugated |
| Immunogen | Recombinant protein of human FBL. |
| Isotype | IgG |
| Form | Liquid |
| Purification | Purified by affinity chromatography. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| UniProt Primary AC | P22087 (UniProt, ExPASy) |
| UniProt Secondary AC | B5BUE8, O75259, Q6IAT5, Q9UPI6 |
| UniProt Entry Name | FBRL_HUMAN |
| Gene Symbol | FBL |
| GeneID | 2091 |
| KEGG | hsa:2091 |
| String | 9606.ENSP00000221801 |
| Molecular Weight | Calculated MW: 33 kDa Observed MW: 36 kDa |
| Buffer | PBS, pH 7.3, 0.02% sodium azide, 50% glycerol. |
| Concentration | > 0.5 mg/ml |
| Availability | Shipped within 5-10 working days. |
| Note | This product is for research use only. |
