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Fibrillarin (FBL) Antibody

Catalogue No: abx001050
Price: £120.00
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Fibrillarin (FBL) Antibody

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FBL Antibody is a Rabbit Polyclonal antibody against FBL. This gene product is a component of a nucleolar small nuclear ribonucleoprotein (snRNP) particle thought to participate in the first step in processing preribosomal RNA. It is associated with the U3, U8, and U13 small nuclear RNAs and is located in the dense fibrillar component (DFC) of the nucleolus. The encoded protein contains an N-terminal repetitive domain that is rich in glycine and arginine residues, like fibrillarins in other species. Its central region resembles an RNA-binding domain and contains an RNP consensus sequence. Antisera from approximately 8% of humans with the autoimmune disease scleroderma recognize fibrillarin.

Target Fibrillarin (FBL)
Clonality Polyclonal
Reactivity Human, Mouse, Monkey
Tested Applications WB, IF/ICC, IP
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200, IP: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human FBL.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P22087 (UniProt, ExPASy)
UniProt Secondary AC B5BUE8, O75259, Q6IAT5, Q9UPI6
UniProt Entry Name FBRL_HUMAN
Gene Symbol FBL
GeneID 2091
KEGG hsa:209
String 9606.ENSP00000221801
Molecular Weight Calculated MW: 33 kDa
Observed MW: 36 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Fibrillarin (FBL) Antibody

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