Forkhead Box Protein O1 (FOXO1) Antibody

FOXO1 Antibody is a Rabbit Polyclonal antibody against FOXO1. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import.

Target	Forkhead Box Protein O1 (FOXO1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat, Monkey
Tested Applications	WB, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 340-580 of human FOXO1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q12778 (UniProt, ExPASy)
UniProt Secondary AC	O43523, Q5VYC7, Q6NSK6
UniProt Entry Name	FOXO1_HUMAN
Gene Symbol	FOXO1
GeneID	2308
NCBI Accession	NP_002006.2
KEGG	hsa:2308
String	9606.ENSP00000368880
Molecular Weight	Calculated MW: 70 kDa Observed MW: 74 kDa
Buffer	PBS, pH 7.3, containing 0.01% thimerosal, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Forkhead Box Protein O1 (FOXO1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue