Forkhead Box Protein O1 (FOXO1) Antibody

Catalogue No: abx002142
Price: £120.00
(Size: 20 µl)
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Forkhead Box Protein O1 (FOXO1) Antibody Forkhead Box Protein O1 (FOXO1) Antibody

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FOXO1 Antibody is a Rabbit Polyclonal antibody against FOXO1. This gene belongs to the forkhead family of transcription factors which are characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it may play a role in myogenic growth and differentiation. Translocation of this gene with PAX3 has been associated with alveolar rhabdomyosarcoma. Interacts with LRPPRC. Interacts with RUNX2; the interaction inhibits RUNX2 transcriptional activity and mediates the IGF1/insulin-dependent BGLAP expression in osteoblasts Interacts with PPP2R1A; the interaction regulates the dephosphorylation of FOXO1 at Thr-24 and Ser-256 leading to its nuclear import.

Target FOXO1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB, IF/ICC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IF/ICC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human FOXO1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q12778 (UniProt, ExPASy)
UniProt Secondary AC O43523, Q5VYC7, Q6NSK6
UniProt Entry Name FOXO1_HUMAN
Gene Symbol FOXO1
GeneID 2308
KEGG hsa:2308
String 9606.ENSP00000368880
Molecular Weight Calculated MW: 69 kDa
Observed MW: 85 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Forkhead Box Protein O1 (FOXO1) Antibody

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