Polypeptide N-Acetylgalactosaminyltransferase 4 (GALNT4) Antibody

Catalogue No: abx003143
Price: £120.00
(Size: 20 µl)
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GALNT4 Antibody is a Rabbit Polyclonal antibody against GALNT4. This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. In vitro, the encoded protein can complement other GalNAc-Ts in the complete O-glycosylation of the mucin-1 tandem repeat and can O-glycosylate the P-selectin glycoprotein ligand-1 molecule. The coding region of this gene is contained within a single exon. Fusion transcripts, which combine part of this gene with the 5' exons of the neighboring POC1B (POC1 centriolar protein homolog B) gene, also exist.

Target GALNT4
Clonality Polyclonal
Reactivity Human, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human GALNT4.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC Q8N4A0 (UniProt, ExPASy)
UniProt Secondary AC B2R775, B4DMX6, O00208
UniProt Entry Name GALT4_HUMAN
Gene Symbol GALNT4
GeneID 8693
KEGG hsa:100528030 hsa:8693
String 9606.ENSP00000436604
Molecular Weight Calculated MW: 45 kDa, 66 kDa
Observed MW: 57 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on GALNT4

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