Menu

Glucokinase (GCK) Antibody

Catalogue No: abx000717
Price: £95.00
Reviews: 0 reviews
(0 reviews)

Click on the image to see the image legend

Available Options

* Size:




GCK Antibody is a Rabbit Polyclonal antibody against GCK. Hexokinases phosphorylate glucose to produce glucose-6-phosphate, the first step in most glucose metabolism pathways. Alternative splicing of this gene results in three tissue-specific forms of glucokinase, one found in pancreatic islet beta cells and two found in liver. The protein localizes to the outer membrane of mitochondria. In contrast to other forms of hexokinase, this enzyme is not inhibited by its product glucose-6-phosphate but remains active while glucose is abundant. Mutations in this gene have been associated with non-insulin dependent diabetes mellitus (NIDDM), maturity onset diabetes of the young, type 2 (MODY2) and persistent hyperinsulinemic hypoglycemia of infancy (PHHI).

Target GCK
Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications IF/ICC
Recommended dilutions IF/ICC: 1/20 - 1/100. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant fusion protein of human GCK.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Molecular Weight Calculated MW: 52 kDa
Swiss Prot P35557
GeneID 2645
Gene Symbol GCK
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Glucokinase (GCK) Antibody

Write a review

Your Name
Your Email Address
PMID
DOI
Type
Your Review

Note: HTML is not translated!

Rating Bad Good


Tags:
(Click to show)