Rhodopsin Kinase (GRK1) Antibody

GRK1 Antibody is a Rabbit Polyclonal antibody against GRK1. This gene encodes a member of the guanine nucleotide-binding protein (G protein)-coupled receptor kinase subfamily of the Ser/Thr protein kinase family. The protein phosphorylates rhodopsin and initiates its deactivation. Defects in GRK1 are known to cause Oguchi disease 2 (also known as stationary night blindness Oguchi type-2). Retina-specific kinase involved in the signal turnoff via phosphorylation of rhodopsin (RHO), the G protein- coupled receptor that initiates the phototransduction cascade. This rapid desensitization is essential for scotopic vision and permits rapid adaptation to changes in illumination.

Target	Rhodopsin Kinase (GRK1)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB, IHC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000, IHC-P: 1/50 - 1/200. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 1-160 of human GRK1.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q15835 (UniProt, ExPASy)
UniProt Secondary AC	Q53X14
UniProt Entry Name	GRK1_HUMAN
Gene Symbol	GRK1
GeneID	6011
NCBI Accession	NP_002920.1
KEGG	hsa:6011
String	9606.ENSP00000334876
Molecular Weight	Calculated MW: 64 kDa Observed MW: 64 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Rhodopsin Kinase (GRK1)

Write a review

Your Name

Your Email Address

PMID

DOI

Your Review

Rating

Continue