Gelsolin (GSN) Antibody

GSN Antibody is a Rabbit Polyclonal antibody against GSN. The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

Target	Gelsolin (GSN)
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat
Tested Applications	WB
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 543-782 of human Gelsolin.
Isotype	IgG
Form	Liquid
Purification	Purified by affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P06396 (UniProt, ExPASy)
UniProt Entry Name	GELS_HUMAN
Gene Symbol	GSN
GeneID	2934
NCBI Accession	NP_000168.1
KEGG	hsa:2934
String	9606.ENSP00000362924
Molecular Weight	Calculated MW: 86 kDa Observed MW: 109 kDa
Buffer	PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol.
Concentration	> 0.2 mg/ml
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on Gelsolin (GSN)

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