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General Transcription Factor IIi (GTF2I) Antibody

Catalogue No: abx000783
Price: £260.00
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GTF2I Antibody is a Rabbit Polyclonal antibody against GTF2I. The GTF2I gene encodes a transcription factor. It negatively regulates agonist-induced calcium entry into cells by interfering with expression of the cation channel TRPC3 at the plasma membrane [PMID: 17023658]. As a transcription factor and/or as a regulator of intracellular calcium levels, GTF2I may play a role in the molecular basis of anxiety[PMID: 22578324]. It interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation [PMID: 16738337].

Target GTF2I
Reactivity Human
Host Rabbit
Clonality Polyclonal
Tested Applications WB, IHC, IF/ICC, FCM
Recommended dilutions WB: 1/200 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Immunogen Recombinant protein of human GTF2I.
Purification Affinity purified.
Form Liquid
Isotype IgG
Conjugation Unconjugated
Storage Aliquot and store at 2°C to 8°C upon receipt.
Molecular Weight Calculated MW: 30 kDa, 107 kDa, 110 kDa, 112 kDa
Observed MW: 140 kDa
Swiss Prot P78347
GeneID 2969
Gene Symbol GTF2I
Concentration > 1 mg/ml
Buffer PBS, pH 7.3, 0.02% sodium azide.
UNSPSC Code 12352203
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on General Transcription Factor IIi (GTF2I) Antibody

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