General Transcription Factor IIi (GTF2I) Antibody

Catalogue No: abx000783
Price: £260.00
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GTF2I Antibody is a Rabbit Polyclonal antibody against GTF2I. The GTF2I gene encodes a transcription factor. It negatively regulates agonist-induced calcium entry into cells by interfering with expression of the cation channel TRPC3 at the plasma membrane [PMID: 17023658]. As a transcription factor and/or as a regulator of intracellular calcium levels, GTF2I may play a role in the molecular basis of anxiety[PMID: 22578324]. It interacts with the basal transcription machinery by coordinating the formation of a multiprotein complex at the C-FOS promoter, and linking specific signal responsive activator complexes. Required for the formation of functional ARID3A DNA-binding complexes and for activation of immunoglobulin heavy-chain transcription upon B-lymphocyte activation [PMID: 16738337].

Target GTF2I
Clonality Polyclonal
Reactivity Human
Tested Applications WB, IHC, IF/ICC, FCM
Host Rabbit
Recommended dilutions WB: 1/200 - 1/2000, IHC: 1/50 - 1/200, IF/ICC: 1/50 - 1/100, FCM: 1/20 - 1/50. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human GTF2I.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at 2°C to 8°C upon receipt.
UniProt Primary AC P78347 (UniProt, ExPASy)
UniProt Entry Name GTF2I_HUMAN
Gene Symbol GTF2I
GeneID 2969
KEGG hsa:296
String 9606.ENSP00000460070
Molecular Weight Calculated MW: 30 kDa, 107 kDa, 110 kDa, 112 kDa
Observed MW: 140 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on General Transcription Factor IIi (GTF2I) Antibody

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