Interferon Beta 1 (IFNB1) Antibody

Catalogue No: abx001326
Price: £120.00
(Size: 20 µl)
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IFNB1 Antibody is a Rabbit Polyclonal antibody against IFNB1. The genes encoding type I interferons (IFNs), which include 14 IFN-å genes, one IFN-∫ gene, one IFN-w (also known as IFN-å II1) gene, and a number of IFN-w pseudogenes, are clustered on human chromosome 9. Interferons-å and -∫ are cytokines that are widely known to induce potent antiviral activity. IFN-å and -∫ exert a variety of other biological effects, including antitumor and immunomodulatory activities and are increasingly used clinically to treat a range of malignancies, myelodysplasias and autoimmune diseases. IFN-w is antigenically different from human IFN-å, IFN-∫ or IFN-©, but is a component of natural mixtures of IFN species produced by virus-induced leukocytes or Burkitt's lymphoma cells. The type I interferon receptor (IFN-åR) interacts with IFN-å, IFN-∫ and IFN-w, and seems to be a multisubunit receptor.

Target IFNB1
Clonality Polyclonal
Reactivity Human, Mouse
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human IFNB1.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P01574 (UniProt, ExPASy)
UniProt Secondary AC Q5VWC9
UniProt Entry Name IFNB_HUMAN
Gene Symbol IFNB1
GeneID 3456
KEGG hsa:3456
String 9606.ENSP00000369581
Molecular Weight Calculated MW: 22 kDa
Observed MW: 20 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 0.5 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on IFNB1

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