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Interleukin 10 Receptor Alpha (IL10RA) Antibody

Catalogue No: abx000418
Price: £220.00
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IL10RA (phospho-Ser319/Ser323) Antibody is a Rabbit Polyclonal antibody against IL10RA (phospho-Ser319/Ser323). The protein encoded by this gene is a receptor for interleukin 10. This protein is structurally related to interferon receptors. It has been shown to mediate the immunosuppressive signal of interleukin 10, and thus inhibits the synthesis of proinflammatory cytokines. This receptor is reported to promote survival of progenitor myeloid cells through the insulin receptor substrate-2/PI 3-kinase/AKT pathway. Activation of this receptor leads to tyrosine phosphorylation of JAK1 and TYK2 kinases. Two transcript variants, one protein-coding and the other not protein-coding, have been found for this gene.

Target IL10RA
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding S319/S323 of human IL10RA.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q13651 (UniProt, ExPASy)
UniProt Secondary AC A8K6I0, B0YJ27
UniProt Entry Name I10R1_HUMAN
Gene Symbol IL10RA
GeneID 3587
String 9606.ENSP00000227752
Molecular Weight Calculated MW: 63 kDa
Observed MW: 63 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Interleukin 10 Receptor Alpha (IL10RA) Antibody

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