Lysine Acetyltransferase 5 (KAT5) Antibody

Catalogue No: abx001864
Price: £230.00
(Size: 50 µl)
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KAT5 Antibody is a Rabbit Polyclonal antibody against KAT5. KAT5 belongs to the MYST protein family that contains atypical zinc finger and histone acetyltransferase domains. Also, KAT5 contains a chromodomain. KAT5 is a catalytic subunit of the NuA4 histone acetyltransferase complex. The NuA4 HAT complex plays a role in transcriptional activation of select genes mainly by acetylation of nucleosomal histone H4 and H2A, which influence nucleosome-DNA interaction and promotes interaction of the modified histones with other proteins that could regulate transcription positively. This complex also involves in the activation of transcriptional programs associated with oncogene and proto-oncogene mediated growth induction, tumor suppressor mediated growth arrest and replicative senescence, DNA repair and apoptosis.

Target KAT5
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB, IHC
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000, IHC: 1/50 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Recombinant protein of human KAT5.
Isotype IgG
Form Liquid
Purification Purified by affinity chromatography.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q92993 (UniProt, ExPASy)
UniProt Entry Name KAT5_HUMAN
Gene Symbol KAT5
GeneID 10524
KEGG hsa:10524
String 9606.ENSP00000340330
Molecular Weight Calculated MW: 53 kDa, 56 kDa, 58 kDa, 61 kDa
Observed MW: 60 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on KAT5

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