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Potassium Voltage-Gated Channel Subfamily A Member 1 (KCNA1) Antibody

Catalogue No: abx002176
Price: £120.00
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Potassium Voltage-Gated Channel Subfamily A Member 1 (KCNA1) Antibody

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KCNA1 Antibody is a Rabbit Polyclonal antibody against KCNA1. This gene encodes a voltage-gated delayed potassium channel that is phylogenetically related to the Drosophila Shaker channel. The encoded protein has six putative transmembrane segments (S1-S6), and the loop between S5 and S6 forms the pore and contains the conserved selectivity filter motif (GYGD). The functional channel is a homotetramer. The N-terminus of the channel is associated with beta subunits that can modify the inactivation properties of the channel as well as affect expression levels. The C-terminus of the channel is complexed to a PDZ domain protein that is responsible for channel targeting. Mutations in this gene have been associated with myokymia with periodic ataxia (AEMK).

Target KCNA1
Clonality Polyclonal
Reactivity Human, Mouse, Rat
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen A synthetic peptide of human KCNA1.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC Q09470 (UniProt, ExPASy)
UniProt Secondary AC A6NM83, Q3MIQ9
UniProt Entry Name KCNA1_HUMAN
Gene Symbol KCNA1
GeneID 3736
KEGG hsa:3736
String 9606.ENSP00000371985
Molecular Weight Calculated MW: 56 kDa
Observed MW: 70 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on Potassium Voltage-Gated Channel Subfamily A Member 1 (KCNA1) Antibody

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