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KDR (pY1059) Antibody

Catalogue No: abx000334
Price: £220.00
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KDR (pY1059) Antibody is a Rabbit Polyclonal antibody against KDR (pY1059). Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Mutations of this gene are implicated in infantile capillary hemangiomas.

Target KDR (pY1059)
Clonality Polyclonal
Reactivity Human
Tested Applications WB
Host Rabbit
Recommended dilutions WB: 1/500 - 1/1000. Optimal dilutions/concentrations should be determined by the end user.
Conjugation Unconjugated
Immunogen Synthetic Peptide. A phospho specific peptide corresponding to residues surrounding Y1059 of human KDR.
Isotype IgG
Form Liquid
Purification Affinity purified.
Storage Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC P35968 (UniProt, ExPASy)
UniProt Secondary AC A2RRS0, B5A925, C5IFA0, O60723, Q14178
UniProt Entry Name VGFR2_HUMAN
Gene Symbol KDR
GeneID 3791
String 9606.ENSP00000263923
Molecular Weight Calculated MW: 75 kDa, 79 kDa, 151 kDa
Observed MW: 230 kDa
Buffer PBS, pH 7.3, 0.02% sodium azide, 50% glycerol.
Concentration > 1 mg/ml
Availability Shipped within 5-10 working days.
Note This product is for research use only.
Research Articles on KDR (pY1059) Antibody

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